A lot of people don’t know this but if thyroid function is low that slows down detoxification as well, so you become more toxic. Fix your hormones to aid in fixing any and everything else in your body AND mind.

Pregnenolone, which is made from cholesterol, gets converted into DHEA, which is then transformed into testosterone or estrogen. Under stress of any form, pregnenolone gets turned into progesterone, which is then converted into cortisol. 

Any type of inflammation or other stressor will cause the release of cortisol to help put out the inflammatory fire. Chronically high cortisol will cause blood sugar fluctuations and inhibit the conversion of T4 to T3. In addition, those blood sugar and insulin fluctuations lead to increased oxidative stress, a very bad situation for your mitochondria. And the decreased T4 to T3 conversion that occurs will lead to a sub-optimal body temperature. When this occurs, your immune function drops significantly. In fact, all of your enzyme functions decline. But if the only solution is to add thyroid hormone or hydrocortisone, the chances of achieving optimal are pretty slim. The adrenals and thyroid are intimately connected. Hormones are like a symphony — each one plays a crucial role. Above, we discussed what elevated cortisol can do. Low cortisol levels are equally dangerous as you’ll be unable to mount an effective immune response or control inflammation. In women, elevated blood sugar will increase testosterone levels. This is one reason why women with PCOS can develop facial hair. In men, high blood sugar will raise estrogen levels. —- Adrenals produce and control cortisol, the stress hormone.

  • Adrenal fatigue comes from chronic stress. When you push your body and mind too hard, your adrenals stop producing cortisol the way they should.
  • a lot of doctors didn’t (and still don’t) recognize adrenal fatigue as real. One big reason is that when your stress response is messed up, it affects so many parts of your biology that it’s hard to identify as adrenal fatigue, and even harder to study.

if you want to be really sure that you have adrenal fatigue, there is a cortisol test that a functional medicine doctor can get you. When you’re stressed, your adrenals release cortisol. If you’re constantly stressed for a long time, you’re constantly producing cortisol, your adrenals become less sensitive to how much cortisol they make, and your stress response and daily cortisol rhythm become irregular.[2][3] That’s when you start to see swings in your mood and energy.